Hypertrophic Cardiomyopathy: A Review

DIFFUSE CORONARY ARTERIAL ECTASIA WITH HYPERTROPHIC CARDIOMYOPATHY

A 40 year old male, a known case of hypertrophic cardiomyopathy, was admitted for catheterization. At catheterization and angiography, septum was hypertrophied to about 5cm and diffuse coronary artery aneurysm was revealed. We found no previous report of coronary artery aneurysm in hypertrophic cardiomyopathy.

Apical Hypertrophic Cardiomyopathy in a Case with Chest Pain and Family History of Sudden Cardiac Death: A Case Report

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease, which is caused by a multitude of mutations in genes encoding proteins of the cardiac sarcomere (1). Apical hypertrophic cardiomyopathy (AHCM) is an uncommon type of HCM. The sudden cardiac death is less likely to occur in the patients inflicted with AHCM (2). Herein, we presented the case of a 29-year-old man ...

بی حسی اپیدورال برای سزارین درخانم مبتلا به بیماری کاردیومیوپاتی هیپرتروفیک-معرفی بیمار

Epidural anesthesia for cesarean section in a patient with Hypertrophic Cardiomyopathy Aim and Background: The pathophysiologic changes of Hypertrophic Cardiomyopathy is complex and the physiologic changes of pregnancy and anesthesia for cesarean section have a great effect in the hemodynamic and it can even lead to maternal death. We report a 21-year pregnant woman with HCM who were candi...

Investigation of Polymorphisms in Non-Coding Region of Human Mitochondrial DNA in 31 Iranian Hypertrophic Cardiomyopathy (HCM) Patients

The D-loop region is a hot spot for mitochondrial DNA (mtDNA) alterations, containing two hypervariable segments, HVS-I and HVS-II. In order to identify polymorphic sites and potential genetic background accounting for Hypertrophic CardioMyopathy (HCM) disease, the complete non-coding region of mtDNA from 31 unrelated HCM patients and 45 normal controls were sequenced. The sequences were aligne...

Genetics of hypertrophic cardiomyopathy: one, two, or more diseases?

PURPOSE OF REVIEW Hypertrophic cardiomyopathy is the most common identifiable cause of sudden death in the young. This review details the history of hypertrophic cardiomyopathy, recent discoveries in its genetic underpinnings and important genotype-phenotype relationships described in recent studies. RECENT FINDINGS Since the discovery of the genetic underpinnings of hypertrophic cardiomyopat...

HYPERTROPHIC CARDIOMYOPATHY ( HCM ) : A Review